{"id":13403,"date":"2017-02-18T20:23:43","date_gmt":"2017-02-18T20:23:43","guid":{"rendered":"http:\/\/newsroom247.com.ng\/?p=13403"},"modified":"2017-02-18T20:23:43","modified_gmt":"2017-02-18T20:23:43","slug":"study-whole-grains-may-lead-to-a-healthier-gut-better-immune-responses","status":"publish","type":"post","link":"http:\/\/newsroom247.com.ng\/?p=13403","title":{"rendered":"STUDY: Whole grains may lead to a healthier gut, better immune responses"},"content":{"rendered":"<p><code><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><br \/>\n<!-- www.deltanewsroom.com --><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block;\" data-ad-client=\"ca-pub-2163942495525027\" data-ad-slot=\"1411897411\" data-ad-format=\"auto\"><\/ins><br \/>\n<script>\n(adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/code><\/p>\n<header>A new study highlights the benefits of eating whole grains over refined grains, after finding that the former may lead to a healthier gut and better immune responses.<\/header>\n<div class=\"photobox_right\"><em>Researchers say that a diet rich in whole grains may benefit the gut and immune system.<\/em><\/div>\n<p>Senior study author Simin Nikbin Meydani, Ph.D., of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, MA, and colleagues report their findings in the <em>American Journal of Clinical Nutrition<\/em>.<\/p>\n<p>There are three components that make up a grain \u2013 the bran, germ, and endosperm. A whole grain contains all three components, whereas a refined grain is processed so that the bran and germ are removed.<\/p>\n<div class=\"code-block code-block-1\"><\/div>\n<p>Whole wheat, oats, rye, barley, brown rice, and quinoa are all examples of whole-grain products, while refined-grain products include wheat flour, white rice, and enriched bread.<\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/www.alternativeadvert.com\/show.php?z=30&amp;pl=12440&amp;ad_type=59&amp;rl=180\" width=\"300\" height=\"250\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>Whole grains are considered a key part of a healthful diet. According to the American Heart Association, they can help to improve cholesterol levels, as well as reduce the risk of obesity, heart disease, stroke, and type 2 diabetes.<\/p>\n<div class=\"code-block code-block-3\"><\/div>\n<p>Previous studies have suggested that whole grains reduce inflammation to produce such benefits. Meydani and colleagues set out to investigate this association further with their new study, noting that research comparing the effects of whole grains and refined grains on immune responses and inflammation has not controlled the diets of participants.<a href=\"http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-13404\" src=\"http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains-300x194.jpg\" alt=\"whole_grains\" width=\"300\" height=\"194\" srcset=\"http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains-300x194.jpg 300w, http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains-768x496.jpg 768w, http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains.jpg 774w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<h2>Whole-grain vs. refined-grain diet<\/h2>\n<p>The 8-week study involved 81 healthy adults, all of whom consumed a Western-style diet high in refined grains for the first 2 weeks.<\/p>\n<p>For the remaining 6 weeks, 40 of the study participants continued with the Western-style diet that was rich in refined grains, while the remaining 41 participants were placed on a Western-style diet that was rich in whole grains.<\/p>\n<p><strong>Importantly, the team notes that the total energy, total fat, and total servings of fruits, vegetables, and proteins were comparable in each diet, meaning that the only difference between the two diets was the type of grains consumed.<\/strong><\/p>\n<p>All meals were preprepared by trained staff in line with the Dietary Guidelines for Americans, and they were designed for weight maintenance. The team explains that this was because previous studies had shown that increasing whole grain intake caused subjects to lose weight, which made it hard to determine whether reduced inflammation was a result of whole-grain consumption or weight loss.<\/p>\n<p>Subjects were required to complete a food checklist with each meal, enabling the researchers to determine how much food each participant ate.<\/p>\n<p>Furthermore, each participant was asked to continue with their usual physical activity, record the occurrence and severity of gastrointestinal symptoms, and refrain from using any anti-inflammatory drugs (such as <em>aspirin<\/em>) in the 72 hours prior to blood samples being taken.<\/p>\n<h2>Whole-grain diet led to increase in memory T cells<\/h2>\n<p>To evaluate how each diet influenced the gut microbiota \u2013 the population of microorganisms in the intestines \u2013 the researchers analyzed participants\u2019 stool samples. Blood samples were also collected, which the team used to assess immune responses.<\/p>\n<p>Compared with participants who consumed the diet rich in refined grains, those who consumed the diet rich in whole grains showed an increase in a type of bacteria called <em>Lachnospira<\/em>, which is known to produce short-chain fatty acids.<\/p>\n<p>The team explains that short-chain fatty acids are important for a healthy immune system.<\/p>\n<p>Furthermore, subjects who consumed the whole-grain diet showed a reduction <em>Enterobacteriaceae<\/em> \u2013 bacteria that trigger inflammation.<\/p>\n<p>The researchers hypothesize that the decrease in <em>Enteorbacteriaceae<\/em> is down to the higher concentration of acetate identified in the stool samples of subjects who consumed the diet rich in whole grains.<\/p>\n<p><strong>On assessing the blood samples of both diet groups, the team found that subjects who consumed the whole-grain diet showed an increase in memory T cells \u2013 types of white blood cells that stave off infection.<\/strong><\/p>\n<p>When immune cells were stimulated with foreign compounds, however, participants who consumed the diet rich in refined grains showed a reduction in the production of TNF-alpha \u2013 a cell signaling protein involved in the first phase of an immune response.<\/p>\n<p><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><br \/>\n<!-- www.deltanewsroom.com --><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block;\" data-ad-client=\"ca-pub-2163942495525027\" data-ad-slot=\"1411897411\" data-ad-format=\"auto\"><\/ins><br \/>\n<script>\n(adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/p>\n<p><code><a href=\"http:\/\/market.jumia.com.ng\/computers-laptops-gaming\/?utm_source=pap&amp;utm_medium=aff&amp;utm_campaign=b364e0f2&amp;a_aid=Omafume&amp;a_bid=b364e0f2\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"\" title=\"\" src=\"\/\/kaymu.postaffiliatepro.com\/accounts\/default1\/a72f75b38\/b364e0f2.png\" alt=\"\" width=\"580\" height=\"249\" \/><\/a><img loading=\"lazy\" decoding=\"async\" style=\"border: 0;\" src=\"http:\/\/kaymu.postaffiliatepro.com\/scripts\/a72f75i38?a_aid=Omafume&amp;a_bid=b364e0f2\" alt=\"\" width=\"1\" height=\"1\" \/><\/code><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study highlights the benefits of eating whole grains over refined grains, after finding that the former may lead to a healthier gut and better immune responses. Researchers say that a diet rich in whole grains may benefit the gut and immune system. Senior study author Simin Nikbin Meydani, Ph.D., of the Jean Mayer [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":13404,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"ngg_post_thumbnail":0,"spay_email":"","footnotes":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false},"categories":[10],"tags":[3532,3533],"class_list":["post-13403","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-healthy-living","tag-simin-nikbin-meydani","tag-whole-grain"],"jetpack_featured_media_url":"http:\/\/newsroom247.com.ng\/wp-content\/uploads\/2017\/02\/whole_grains.jpg","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4oswh-3ub","_links":{"self":[{"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/posts\/13403","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13403"}],"version-history":[{"count":1,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/posts\/13403\/revisions"}],"predecessor-version":[{"id":13405,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/posts\/13403\/revisions\/13405"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=\/wp\/v2\/media\/13404"}],"wp:attachment":[{"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13403"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/newsroom247.com.ng\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}